ZFIN ID: ZDB-GENE-080204-124
Gene Name: F-box protein 2
Gene Symbol: fbxo2    Nomenclature History

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Previous Name: zgc:175088

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; glycoprotein catabolic process; and ubiquitin-dependent ERAD pathway. Predicted to localize to SCF ubiquitin ligase complex and cytoplasm. Is expressed in EVL; periderm; and polster. Orthologous to human FBXO2 (F-box protein 2).
Genome Resources: Alliance (1),  Gene:559776 (1),  Ensembl(GRCz11):ENSDARG00000099306 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [IMAGE:7160126]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH fbxo2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH fbxo2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process glycoprotein catabolic process (more)
Cellular Component cytoplasm (more)
Molecular Function CONTRIBUTES_TO   ubiquitin protein ligase activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA zgc:175088-201 (1)    Ensembl 1054
ncRNA zgc:175088-002 (1) 1013
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fbxo2 No data available
MARKER RELATIONSHIPS
fbxo2 Encodes: [EST] IMAGE:7160126 (1)
[cDNA] MGC:175088 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001113798 (1) 1140 nt
Polypeptide UniProtKB:A3KP76 (1) 185 aa
Sequence Information (all 12)
ORTHOLOGY for fbxo2 ( Chr: 11 )
CITATIONS (13)