ZFIN is now using GRCz12tu for Genomic Data
Gene
dock5
- ID
- ZDB-GENE-080108-4
- Name
- dedicator of cytokinesis 5
- Symbol
- dock5 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Acts upstream of or within myoblast fusion. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human DOCK5 (dedicator of cytokinesis 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Moore et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Moore et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR027007 | C2 DOCK-type domain |
| Domain | IPR027357 | DOCKER domain |
| Domain | IPR032376 | Dedicator of cytokinesis, N-terminal domain |
| Domain | IPR046769 | DOCKER, Lobe A |
| Domain | IPR046770 | DOCKER, Lobe B |
| Domain | IPR046773 | DOCKER, Lobe C |
| Domain | IPR047025 | Dedicator of cytokinesis protein 1/5, SH3 domain |
| Domain | IPR056372 | Dedicator of cytokinesis, TPR repeats region |
| Family | IPR026791 | Dedicator of cytokinesis |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR042455 | Dedicator of cytokinesis, N-terminal, subdomain 1 |
| Homologous_superfamily | IPR043161 | Dedicator of cytokinesis, C-terminal, lobe A |
| Homologous_superfamily | IPR043162 | Dedicator of cytokinesis, C-terminal, lobe C |
Domain Details Per Protein
| Protein | Additional Resources | Length | Armadillo-type fold | C2 DOCK-type domain | C2 domain superfamily | Dedicator of cytokinesis | Dedicator of cytokinesis, C-terminal, lobe A | Dedicator of cytokinesis, C-terminal, lobe C | Dedicator of cytokinesis, N-terminal domain | Dedicator of cytokinesis, N-terminal, subdomain 1 | Dedicator of cytokinesis protein 1/5, SH3 domain | Dedicator of cytokinesis, TPR repeats region | DOCKER domain | DOCKER, Lobe A | DOCKER, Lobe B | DOCKER, Lobe C | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A8E1V7 | InterPro | 1867 | ||||||||||||||||
| UniProtKB:A0AB32TUD8 | InterPro | 1867 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers