Gene
il23r
- ID
- ZDB-GENE-080107-5
- Name
- interleukin 23 receptor
- Symbol
- il23r Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to localize to external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); inflammatory bowel disease (multiple); pulmonary hypertension; rhinitis; and systemic scleroderma. Orthologous to human IL23R (interleukin 23 receptor).
- Genome Resources
- Note
- None
- All Expression Data
- from Liongue et al., 2007
- Cross-Species Comparison
- High Throughput Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| inflammatory bowel disease 17 | Alliance | {Inflammatory bowel disease 17, protection against} | 612261 |
| psoriasis 7 | Alliance | {Psoriasis, protection against} | 605606 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold |
|---|---|---|---|---|
|
UniProtKB:F8W4N2
|
817 | |||
|
UniProtKB:A8WH98
|
818 | |||
|
UniProtKB:F8W454
|
857 |
Interactions and Pathways
No data available
Plasmids
No data available