Gene

il23r

ID
ZDB-GENE-080107-5
Name
interleukin 23 receptor
Symbol
il23r Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to localize to external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); inflammatory bowel disease (multiple); pulmonary hypertension; rhinitis; and systemic scleroderma. Orthologous to human IL23R (interleukin 23 receptor).
Genome Resources
Note
None
Expression
All Expression Data
from Liongue et al., 2007
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With il23r Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
inflammatory bowel disease 17 Alliance {Inflammatory bowel disease 17, protection against} 612261
psoriasis 7 Alliance {Psoriasis, protection against} 605606
Associated With il23r Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003961 Fibronectin type III
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold
UniProtKB:F8W4N2 817
UniProtKB:A8WH98 818
UniProtKB:F8W454 857
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations