Gene
il23r
- ID
- ZDB-GENE-080107-5
- Name
- interleukin 23 receptor
- Symbol
- il23r Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and positive regulation of cell population proliferation. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); bone disease (multiple); inflammatory bowel disease (multiple); pulmonary hypertension; and systemic scleroderma. Orthologous to human IL23R (interleukin 23 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liongue et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| inflammatory bowel disease 17 | Alliance | {Inflammatory bowel disease 17, protection against} | 612261 |
| psoriasis 7 | Alliance | {Psoriasis, protection against} | 605606 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Type I Cytokine Receptor Family, Type 2 Subfamily |
|---|---|---|---|---|---|---|
| UniProtKB:F8W454 | InterPro | 857 | ||||
| UniProtKB:A8WH98 | InterPro | 818 |
Interactions and Pathways
No data available
Plasmids
No data available