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ZIRC
ZFIN ID: ZDB-GENE-080107-5
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Gene Name: interleukin 23 receptor
Gene Symbol: il23r    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have interleukin-11 binding activity and interleukin-11 receptor activity. Predicted to be involved in positive regulation of cell population proliferation. Predicted to localize to the external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; autoimmune hypersensitivity disease (multiple); bone inflammation disease (multiple); inflammatory bowel disease (multiple); and psoriasis (multiple). Orthologous to human IL23R (interleukin 23 receptor).
Genome Resources: Alliance (1),  Gene:100134972 (1),  Ensembl(GRCz11):ENSDARG00000052158 (1)
GENE EXPRESSION
All Expression Data: text only from Liongue et al., 2007
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20741 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa33896 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa40728 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-il23r N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH il23r HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    inflammatory bowel disease 17 Alliance {Inflammatory bowel disease 17, protection against} 612261
    psoriasis 7 Alliance {Psoriasis, protection against} 605606
    DISEASE ASSOCIATED WITH il23r VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    Molecular Function cytokine binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003961 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR036116 (1)
  • PROSITE:PS50853 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA il23r-201 (1)    Ensembl 2451
    Select Tool
    il23r-202 (1)    Ensembl 3653
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM il23r No data available
    MARKER RELATIONSHIPS
    il23r Contained in: [BAC] DKEYP-63D11
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113506 (1) 2457 bp
    Select Tool
    Genomic GenBank:BX323033 (1) 171058 bp
    Select Tool
    Polypeptide UniProtKB:F8W454 (1) 857 aa
    Select Tool
    Sequence Clusters UniGene:143228 (1)
    Sequence Information (all 12)
    ORTHOLOGY for il23r ( Chr: 6 )
    CITATIONS (14)