Gene
mst1ra
- ID
- ZDB-GENE-071218-2
- Name
- macrophage stimulating 1 receptor a
- Symbol
- mst1ra Nomenclature History
- Previous Names
-
- mst1r
- RON (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in several processes, including positive regulation of kinase activity; positive regulation of protein kinase B signaling; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to basal plasma membrane; integral component of plasma membrane; and receptor complex. Is expressed in gill and intestine. Orthologous to human MST1R (macrophage stimulating 1 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Huitema et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Nasopharyngeal carcinoma, susceptibility to, 3} | 617075 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008266 | Tyrosine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR001627 | Sema domain |
| Domain | IPR002909 | IPT domain |
| Domain | IPR016201 | PSI domain |
| Domain | IPR020635 | Tyrosine-protein kinase, catalytic domain |
| Family | IPR016244 | Tyrosine-protein kinase, HGF/MSP receptor |
| Family | IPR031148 | Plexin family |
| Family | IPR050122 | Receptor Tyrosine Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036352 | Sema domain superfamily |
| Repeat | IPR002165 | Plexin repeat |
Domain Details Per Protein
| Protein | Length | Immunoglobulin E-set | Immunoglobulin-like fold | IPT domain | Plexin family | Plexin repeat | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | PSI domain | Receptor Tyrosine Kinase | Sema domain | Sema domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, active site | Tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, HGF/MSP receptor | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3BAK5
|
680 | |||||||||||||||||
|
UniProtKB:E7EYX4
|
1350 | |||||||||||||||||
|
UniProtKB:A0A8M2BDJ7
|
1356 | |||||||||||||||||
|
UniProtKB:A0A8M3ATL8
|
706 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mst1ra-201
(1)
|
Ensembl | 4,722 nt |
Interactions and Pathways
No data available
Plasmids
No data available