Gene

spint1b

ID
ZDB-GENE-071218-1
Name
serine peptidase inhibitor, Kunitz type 1 b
Symbol
spint1b Nomenclature History
Previous Names
  • hai1b (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within epidermis development. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in gut; lateral line primordium; and primitive olfactory epithelium. Orthologous to human SPINT1 (serine peptidase inhibitor, Kunitz type 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Carney et al., 2007
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spint1b Human Ortholog
No data available
Associated With spint1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
Conserved_site IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
Domain IPR002223 Pancreatic trypsin inhibitor Kunitz domain
Domain IPR011106 Seven cysteines, N-terminal
Domain IPR013980 MANSC domain
Domain IPR022409 PKD/Chitinase domain
Family IPR042482 Kunitz-type protease inhibitor 1
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR035986 PKD domain superfamily
Homologous_superfamily IPR036055 LDL receptor-like superfamily
Homologous_superfamily IPR036880 Pancreatic trypsin inhibitor Kunitz domain superfamily
Repeat IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Domain Details Per Protein
Protein Length Immunoglobulin-like fold Kunitz-type protease inhibitor 1 LDL receptor-like superfamily Low-density lipoprotein (LDL) receptor class A, conserved site Low-density lipoprotein (LDL) receptor class A repeat MANSC domain Pancreatic trypsin inhibitor Kunitz domain Pancreatic trypsin inhibitor Kunitz domain superfamily PKD/Chitinase domain PKD domain superfamily Proteinase inhibitor I2, Kunitz, conserved site Seven cysteines, N-terminal
UniProtKB:F1QXZ6 499
UniProtKB:A9JR82 499
UniProtKB:A7XDE0 452
UniProtKB:B3DKP8 501
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations