ZFIN ID: ZDB-GENE-071218-1
Gene Name: serine peptidase inhibitor, Kunitz type 1 b
Gene Symbol: spint1b    Nomenclature History

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Previous Name: hai1b (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase inhibitor activity. Involved in epidermis development. Predicted to localize to integral component of membrane. Is expressed in gut; lateral line primordium; and primitive olfactory epithelium. Orthologous to human SPINT1 (serine peptidase inhibitor, Kunitz type 1).
Genome Resources: Alliance (1),  Gene:797346 (1),  Ensembl(GRCz11):ENSDARG00000012467 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Carney et al., 2007
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa3058 Point Mutation Unknown Premature Stop ENU
sa8501 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29296 Point Mutation Unknown Splice Site ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-spint1b N/A 2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH spint1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH spint1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process epidermis development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function serine-type endopeptidase inhibitor activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA spint1b-201 (1)    Ensembl 2436
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM spint1b No data available
    MARKER RELATIONSHIPS
    spint1b Contained in: [Fosmid] ZFOS-692B10 (1)
    spint1b Encodes: [cDNA] MGC:171440 (1), MGC:195361 (1), MGC:195373 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001111223 (1)
    Genomic GenBank:CU693438 (1) 46842 nt
    Select Tool
    Polypeptide UniProtKB:B3DKP8 (1) 501 aa
    Sequence Information (all 20)
    ORTHOLOGY for spint1b ( Chr: 20 )
    CITATIONS (17)