recql5

ID

ZDB-GENE-071214-1

Name

RecQ helicase-like 5

Symbol

recql5 Nomenclature History

Previous Names

recql5l

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable 3'-5' DNA helicase activity and four-way junction helicase activity. Acts upstream of or within negative regulation of mitotic recombination. Predicted to be active in chromosome; cytoplasm; and nucleus. Is expressed in several structures, including otic vesicle; pericardial region; presumptive neural retina; retina; and ventricular system. Orthologous to human RECQL5 (RecQ like helicase 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Xie et al., 2007

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With recql5 Human Ortholog

No data available

Associated With recql5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR010716	RecQ helicase-like 5
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR013257	Set2 Rpb1 interacting domain
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR032284	ATP-dependent DNA helicase RecQ, zinc-binding domain
Family	IPR004589	DNA helicase, ATP-dependent, RecQ type
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase