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Gene

itgb8

ID
ZDB-GENE-071213-3
Name
integrin, beta 8
Symbol
itgb8 Nomenclature History
Previous Names
  • si:ch1073-83d9.2
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable integrin binding activity. Acts upstream of or within angiogenesis and endothelial cell proliferation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of integrin complex. Predicted to be active in cell surface and focal adhesion. Is expressed in head. Orthologous to human ITGB8 (integrin subunit beta 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Liu et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itgb8 Human Ortholog
No data available
Associated With itgb8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002369 Integrin beta subunit, VWA domain
Domain IPR012896 Integrin beta subunit, tail
Domain IPR013111 EGF-like domain, extracellular
Domain IPR016201 PSI domain
Domain IPR033760 Integrin beta N-terminal
Family IPR015442 Integrin beta-8 subunit
Family IPR015812 Integrin beta subunit
Homologous_superfamily IPR032695 Integrin domain superfamily
Homologous_superfamily IPR036349 Integrin beta tail domain superfamily
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
Domain Details Per Protein
Protein Length EGF-like domain, extracellular Integrin beta-8 subunit Integrin beta N-terminal Integrin beta subunit Integrin beta subunit, tail Integrin beta subunit, VWA domain Integrin beta tail domain superfamily Integrin domain superfamily PSI domain von Willebrand factor A-like domain superfamily
UniProtKB:A0A2R8RTX7 668
UniProtKB:F1QN46 632
UniProtKB:A3RI57 282
UniProtKB:A0A2L1ISY2 156
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations