Gene
flii
- ID
- ZDB-GENE-071212-3
- Name
- FLII actin remodeling protein
- Symbol
- flii Nomenclature History
- Previous Names
-
- im:7141769
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in sarcomere organization. Predicted to localize to actin cytoskeleton; cytoplasm; and nucleus. Is expressed in myotome. Orthologous to human FLII (FLII actin remodeling protein).
- Genome Resources
- Note
- None
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Naganawa et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR007123 | Gelsolin-like domain |
Family | IPR007122 | Villin/Gelsolin |
Family | IPR029919 | Protein flightless-1 |
Homologous_superfamily | IPR029006 | ADF-H/Gelsolin-like domain superfamily |
Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
Homologous_superfamily | IPR036180 | Gelsolin-like domain superfamily |
Repeat | IPR001611 | Leucine-rich repeat |
Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Repeat | IPR025875 | Leucine rich repeat 4 |
Domain Details Per Protein
Protein | Length | ADF-H/Gelsolin-like domain superfamily | Gelsolin-like domain | Gelsolin-like domain superfamily | Leucine-rich repeat | Leucine rich repeat 4 | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype | Protein flightless-1 | Villin/Gelsolin |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:F8WK50
|
1259 | |||||||||
UniProtKB:X1WE86
|
1259 |
Interactions and Pathways
No data available
Plasmids
No data available