Gene

flii

ID

ZDB-GENE-071212-3

Name

FLII actin remodeling protein

Symbol

flii Nomenclature History

Previous Names

im:7141769

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in sarcomere organization. Predicted to localize to actin cytoskeleton; cytoplasm; and nucleus. Is expressed in myotome. Orthologous to human FLII (FLII actin remodeling protein).

Genome Resources

Note

None

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Naganawa et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With flii Human Ortholog

No data available

Associated With flii Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR007123	Gelsolin-like domain
Family	IPR007122	Villin/Gelsolin
Family	IPR029919	Protein flightless-1
Homologous_superfamily	IPR029006	ADF-H/Gelsolin-like domain superfamily
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036180	Gelsolin-like domain superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype
Repeat	IPR025875	Leucine rich repeat 4