ZFIN ID: ZDB-GENE-071212-3
Gene Name: FLII actin remodeling protein
Gene Symbol: flii    Nomenclature History

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Previous Name: im:7141769

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Involved in sarcomere organization. Predicted to localize to actin cytoskeleton; cytoplasm; and nucleus. Is expressed in myotome. Orthologous to human FLII (FLII actin remodeling protein).
Genome Resources: Alliance (1),  Gene:560281 (1),  Ensembl(GRCz11):ENSDARG00000059701 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7141769]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
mi372 Point Mutation Acceptor Splice Site of Exon 5 Premature Stop ENU
sa9399 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12788 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-flii N/A 1
    DISEASE ASSOCIATED WITH flii HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH flii VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process sarcomere organization (more)
    Cellular Component actin cytoskeleton (more)
    Molecular Function actin filament binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA flii-201 (1)    Ensembl 5403
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM flii No data available
    MARKER RELATIONSHIPS
    flii Contained in: [BAC] DKEY-19E10 (1) (order this)
    flii Encodes: [EST] IMAGE:7141769 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001257146 (1) 3878 nt
    Genomic GenBank:BX649547 (1) 237569 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F8WK50 (1) 1259 aa
    Sequence Information (all 10)
    ORTHOLOGY for flii ( Chr: 3 )
    CITATIONS (20)