Gene

ifnphi3

ID

ZDB-GENE-071128-2

Name

interferon phi 3

Symbol

ifnphi3 Nomenclature History

Previous Names

ifn3

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have cytokine activity and cytokine receptor binding activity. Involved in defense response to virus. Predicted to localize to extracellular space. Is expressed in spleen. Human ortholog(s) of this gene implicated in COVID-19; Crimean-Congo hemorrhagic fever; hepatitis B; liver disease (multiple); and sarcoidosis. Orthologous to several human genes including IFNA10 (interferon alpha 10); IFNA14 (interferon alpha 14); and IFNA16 (interferon alpha 16).

Genome Resources

Alliance (1)
Ensembl(GRCz11):ENSDARG00000070676 (1)

Note

None

Expression

All Expression Data

8 figures from 7 publications

Cross-Species Comparison

High Throughput Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ifnphi3 Human Ortholog

No data available

Associated With ifnphi3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR000471	Interferon alpha/beta/delta
Homologous_superfamily	IPR009079	Four-helical cytokine-like, core

Domain Details Per Protein

Protein	Length	Four-helical cytokine-like, core	Interferon alpha/beta/delta
UniProtKB:A0A2R8Q8C3 InterPro	182
UniProtKB:A0A2R8RL48 InterPro	77
UniProtKB:A0A2R8Q764 InterPro	55
UniProtKB:A8E6E3 InterPro	181

Transcripts

Genome Browsers: No data available

No data available

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Ensembl Gene Tree

Citations