ZFIN ID: ZDB-GENE-071120-3
Gene Name: Tnf receptor-associated factor 5
Gene Symbol: traf5    Nomenclature History

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Previous Name: si:ch211-284e20.7

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have enzyme binding activity; tumor necrosis factor receptor binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in protein K63-linked ubiquitination; regulation of intracellular signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to localize to cytoplasmic side of plasma membrane and plasma membrane signaling receptor complex. Orthologous to human TRAF5 (TNF receptor associated factor 5).
Genome Resources: Alliance (1),  Gene:563887 (1),  Ensembl(GRCz11):ENSDARG00000017240 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15889 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH traf5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH traf5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of I-kappaB kinase/NF-kappaB signaling (more)
    Cellular Component cytoplasmic side of plasma membrane (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA traf5-202 (1)    Ensembl 1011
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM traf5 No data available
    MARKER RELATIONSHIPS
    traf5 Contained in: [BAC] CH211-284E20 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_021469653 (1)
    Genomic GenBank:AL954145 (1) 160871 nt
    Select Tool
    Polypeptide UniProtKB:F6NY94 (1) 305 aa
    Sequence Information (all 8)
    ORTHOLOGY for traf5 ( Chr: 22 )
    CITATIONS (21)