Gene

nes

ID
ZDB-GENE-071119-2
Name
nestin
Symbol
nes Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable intermediate filament binding activity. Acts upstream of or within embryonic camera-type eye development; negative regulation of apoptotic process; and nervous system development. Predicted to be located in intermediate filament. Is expressed in several structures, including adaxial cell; gut epithelium; nervous system; neural crest cell; and neuronal stem cell. Orthologous to human NES (nestin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
29 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Chen et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nes Human Ortholog
No data available
Associated With nes Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR039008 Intermediate filament, rod domain
Family IPR031211 Nestin
Homologous_superfamily IPR042180 Intermediate filament, rod domain, coil 1B
Domain Details Per Protein
Protein Length Intermediate filament protein, conserved site Intermediate filament, rod domain Intermediate filament, rod domain, coil 1B Nestin
UniProtKB:P86839
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations