Gene
caskin1
- ID
- ZDB-GENE-071115-3
- Name
- CASK interacting protein 1
- Symbol
- caskin1 Nomenclature History
- Previous Names
-
- si:dkey-34b22.2
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to be located in cytoplasm. Orthologous to human CASKIN1 (CASK interacting protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa9831 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa14718 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa20075 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa20076 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa26107 | Allele with one point mutation | Unknown | Unknown | ENU | |
| sa33234 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa45143 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat and SAM domain-containing protein 1/Caskin | Ankyrin repeat-containing domain superfamily | Caskin1/2, SAM repeat 1 | Caskin1/2, SAM repeat 2 | Caskin-1, CASK-interaction domain | Caskin, C-terminal | SH3 domain | SH3-like domain superfamily | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AR19 | InterPro | 1434 | |||||||||||
| UniProtKB:A0A8M3AY61 | InterPro | 1511 | |||||||||||
| UniProtKB:A0A8M3AR14 | InterPro | 1520 | |||||||||||
| UniProtKB:A0A8M3AQS1 | InterPro | 1476 | |||||||||||
| UniProtKB:A0A8M9Q5E2 | InterPro | 1441 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
caskin1-201
(1)
|
Ensembl | 4,194 nt | ||
| mRNA |
caskin1-202
(1)
|
Ensembl | 15,937 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-34B22 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068219192 (1) | 11127 nt | ||
| Genomic | GenBank:BX572621 (2) | 196336 nt | ||
| Polypeptide | UniProtKB:A0AB32TL61 (1) | 1562 aa |
- Comparative Orthology
- Alliance
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Liongue, C., and Ward, A.C. (2007) Evolution of Class I cytokine receptors. BMC Evolutionary Biology. 7(1):120
- Lo, J., Lee, S., Xu, M., Liu, F., Ruan, H., Eun, A., He, Y., Ma, W., Wang, W., Wen, Z., and Peng, J. (2003) 15,000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Genome research. 13(3):455-466
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