ZFIN is now using GRCz12tu for Genomic Data
Gene
adam10b
- ID
- ZDB-GENE-071115-1
- Name
- ADAM metallopeptidase domain 10b
- Symbol
- adam10b Nomenclature History
- Previous Names
-
- zgc:64203
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm; organelle; and plasma membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease 18 and reticulate acropigmentation of Kitamura. Orthologous to human ADAM10 (ADAM metallopeptidase domain 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Alzheimer's disease 18 | Alliance | {Alzheimer disease 18, susceptibility to} | 615590 |
| reticulate acropigmentation of Kitamura | Alliance | Reticulate acropigmentation of Kitamura | 615537 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M9PGZ4 | InterPro | 669 |
| UniProtKB:A0AC58IUQ3 | InterPro | 1018 |
| UniProtKB:A0AC36K2J0 | InterPro | 780 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adam10b-201
(1)
|
Ensembl | 1,800 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers