Gene

dntt

ID
ZDB-GENE-071020-1
Name
deoxynucleotidyltransferase, terminal
Symbol
dntt Nomenclature History
Previous Names
  • TdT (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have DNA-directed DNA polymerase activity. Predicted to be involved in base-excision repair and double-strand break repair via nonhomologous end joining. Predicted to localize to nucleus. Is expressed in intestine; kidney; spleen; and thymus.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Beetz et al., 2007
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dntt Human Ortholog
No data available
Associated With dntt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR019843 DNA polymerase family X, binding site
Domain IPR001357 BRCT domain
Domain IPR002054 DNA-directed DNA polymerase X
Domain IPR010996 DNA polymerase beta-like, N-terminal domain
Domain IPR018944 DNA polymerase lambda, fingers domain
Domain IPR028207 DNA polymerase beta, palm domain
Domain IPR029398 DNA polymerase beta, thumb domain
Family IPR001726 DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu
Family IPR022312 DNA polymerase family X
Family IPR027249 DNA-directed DNA/RNA polymerase mu
Family IPR027292 DNA nucleotidylexotransferase (TdT)
Homologous_superfamily IPR027421 DNA polymerase lambda lyase domain superfamily
Homologous_superfamily IPR036420 BRCT domain superfamily
Homologous_superfamily IPR037160 DNA polymerase, thumb domain superfamily
Homologous_superfamily IPR043519 Nucleotidyltransferase superfamily
Domain Details Per Protein
Protein Length BRCT domain BRCT domain superfamily DNA-directed DNA polymerase X DNA-directed DNA/RNA polymerase mu DNA nucleotidylexotransferase (TdT) DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu DNA polymerase beta-like, N-terminal domain DNA polymerase beta, palm domain DNA polymerase beta, thumb domain DNA polymerase family X DNA polymerase family X, binding site DNA polymerase lambda, fingers domain DNA polymerase lambda lyase domain superfamily DNA polymerase, thumb domain superfamily Nucleotidyltransferase superfamily
UniProtKB:Q5J2Q9 487
UniProtKB:B3DKA1 486
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations