ZFIN ID: ZDB-GENE-071008-4
Gene Name: autoimmune regulator
Gene Symbol: aire
Sequence Ontology ID : SO:0000704

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Previous Name: si:dkey-261l2.5

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1404 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17261 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-aire (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH aire HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autoimmune polyendocrine syndrome type 1 Autoimmune polyendocrinopathy syndrome , type I, with or without reversible metaphyseal dysplasia 240300
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process humoral immune response (more)
    Cellular Component cytoplasm (more)
    Molecular Function DNA binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000770 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR004865 (1)
  • InterPro:IPR008087 (1)
  • InterPro:IPR010919 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50864 (1)
  • PROSITE:PS51414 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF03172 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA aire-001 (1) 1796
    aire-002 (1) 665
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM aire No data available
    MARKER RELATIONSHIPS
    aireContained in: [BAC] DKEY-261L2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110014 (1) 1821bp
    Genomic GenBank:BX649390 (1) 184594bp
    Select Tool
    Polypeptide UniProtKB:F1Q623 (1) 515aa
    Sequence Clusters UniGene:113878 (1)
    Sequence Information (all 14)
    OTHER aire GENE PAGES
  • Alliance (1)
  • Gene:100007662 (1)
  • VEGA:OTTDARG00000021525 (1)
  • Ensembl(GRCz10):ENSDARG00000056784 (1)
  • ORTHOLOGY for aire (Chr: 2)
    CITATIONS (15)