Gene

fgf1b

ID
ZDB-GENE-071004-7
Name
fibroblast growth factor 1b
Symbol
fgf1b Nomenclature History
Previous Names
  • zgc:136885
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable fibroblast growth factor receptor binding activity; growth factor activity; and heparin binding activity. Predicted to act upstream of or within several processes, including angiogenesis; fibroblast growth factor receptor signaling pathway; and positive regulation of cell division. Predicted to be located in several cellular components, including cell cortex; cytosol; and extracellular region. Human ortholog(s) of this gene implicated in brain ischemia; cleft lip; myocardial infarction; schizophrenia; and urinary bladder cancer. Orthologous to human FGF1 (fibroblast growth factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Lazcano et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fgf1b Human Ortholog
No data available
Associated With fgf1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002209 Fibroblast growth factor family
Family IPR028210 Fibroblast growth factor 1
Homologous_superfamily IPR008996 Cytokine IL1/FGF
Domain Details Per Protein
Protein Length Cytokine IL1/FGF Fibroblast growth factor 1 Fibroblast growth factor family
UniProtKB:F1QC94 102
UniProtKB:A7YT71 158
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations