ZFIN ID: ZDB-GENE-071004-41
Gene Name: microtubule-associated protein, RP/EB family, member 2
Gene Symbol: mapre2    Nomenclature History

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Previous Name: zgc:171788 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have microtubule plus-end binding activity. Involved in embryonic cranial skeleton morphogenesis. Predicted to localize to the microtubule cytoskeleton. Orthologous to human MAPRE2 (microtubule associated protein RP/EB family member 2).
Genome Resources: Alliance (1),  Gene:557679 (1),  Ensembl(GRCz11):ENSDARG00000099943 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa669 Point Mutation Unknown Premature Stop ENU
sa24540 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mapre2 N/A 1
    MO2-mapre2 N/A 1
    DISEASE ASSOCIATED WITH mapre2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Symmetric circumferential skin creases, congenital, 2 616734
    DISEASE ASSOCIATED WITH mapre2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic cranial skeleton morphogenesis (more)
    Cellular Component microtubule (more)
    Molecular Function microtubule binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001715 Calponin homology domain
    Domain IPR004953 EB1, C-terminal
    Family IPR027328 Microtubule-associated protein RP/EB
    Family IPR027735 EB2, vertebrate
    Homologous_superfamily IPR036133 EB1, C-terminal domain superfamily
    Homologous_superfamily IPR036872 CH domain superfamily
    Homologous_superfamily IPR042180 Intermediate filament, rod domain, coil 1B
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mapre2-201 (1)    Ensembl 639
    mapre2-203 (1)    Ensembl 1366
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mapre2 No data available
    MARKER RELATIONSHIPS
    mapre2 Contained in: [BAC] CH211-176D9 (1)
    mapre2 Encodes: [cDNA] MGC:171788 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001109702 (1) 1734 nt
    Genomic GenBank:BX005079 (1) 157845 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IQR0 (1) 386 aa
    Sequence Information (all 14)
    ORTHOLOGY for mapre2 ( Chr: 24 )
    CITATIONS (18)