Gene
rnf34b
- ID
- ZDB-GENE-071004-31
- Name
- ring finger protein 34b
- Symbol
- rnf34b Nomenclature History
- Previous Names
-
- zgc:171755
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol; endomembrane system; and nuclear speck. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human RNF34 (ring finger protein 34).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR049320 | E3 ubiquitin-protein ligase CARP1/2, FYVE/PHD zinc finger |
| Domain | IPR049323 | E3 ubiquitin-protein ligase CARP1, FYVE/PHD zinc finger |
| Family | IPR051728 | RING-FYVE domain-containing E3 ubiquitin-protein ligase |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036361 | SAP domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | E3 ubiquitin-protein ligase CARP1/2, FYVE/PHD zinc finger | E3 ubiquitin-protein ligase CARP1, FYVE/PHD zinc finger | RING-FYVE domain-containing E3 ubiquitin-protein ligase | SAP domain superfamily | Zinc finger, FYVE/PHD-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A7MBY3 | InterPro | 377 | |||||||
| UniProtKB:A0A8M2B9I4 | InterPro | 398 | |||||||
| UniProtKB:F1RCH2 | InterPro | 384 | |||||||
| UniProtKB:A0AB32TVX2 | InterPro | 391 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rnf34b-201
(1)
|
Ensembl | 1,575 nt | ||
| mRNA |
rnf34b-202
(1)
|
Ensembl | 1,377 nt |
Interactions and Pathways
No data available
Plasmids
No data available