ZFIN ID: ZDB-GENE-071004-15
Gene Name: glypican 6a
Gene Symbol: gpc6a    Nomenclature History

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Previous Names: si:ch1073-86a3.1, zgc:171629 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to be involved in several processes, including regulation of neurotransmitter receptor localization to postsynaptic specialization membrane; regulation of presynapse assembly; and synaptic membrane adhesion. Predicted to localize to cell surface; extracellular region; and synapse. Is expressed in blastomere and nervous system. Human ortholog(s) of this gene implicated in omodysplasia. Orthologous to human GPC6 (glypican 6).
Genome Resources: Alliance (1),  Gene:571904 (1),  Ensembl(GRCz11):ENSDARG00000103156 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gpc6a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
omodysplasia Alliance Omodysplasia 1 258315
DISEASE ASSOCIATED WITH gpc6a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of signal transduction (more)
Cellular Component anchored component of membrane (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA gpc6a-001 (1) 410
gpc6a-002 (1) 404
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM gpc6a No data available
MARKER RELATIONSHIPS
gpc6a Contained in: [BAC] CH73-271A5 (1), CH73-380P12 (1)
[Fosmid] CH1073-86A3 (1)
gpc6a Encodes: [cDNA] MGC:171629 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001109719 (1) 2061 nt
Genomic GenBank:CU986306 (1) 82823 nt
Select Tool
Polypeptide UniProtKB:A7MBT1 (1) 562 aa
Sequence Information (all 50)
ORTHOLOGY for gpc6a ( Chr: 1 )
CITATIONS (17)