ZFIN ID: ZDB-GENE-070928-13
Gene Name: poly(A) specific ribonuclease subunit PAN3
Gene Symbol: pan3    Nomenclature History

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Previous Name: zgc:171628

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to contribute to poly(A)-specific ribonuclease activity. Predicted to be involved in deadenylation-dependent decapping of nuclear-transcribed mRNA; nuclear-transcribed mRNA poly(A) tail shortening; and positive regulation of cytoplasmic mRNA processing body assembly. Predicted to localize to the P-body and PAN complex. Orthologous to human PAN3 (poly(A) specific ribonuclease subunit PAN3).
Genome Resources: Alliance (1),  Gene:100126012 (1),  Ensembl(GRCz11):ENSDARG00000031637 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014539Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022914Tg Transgenic Insertion Unknown Unknown DNA
    sa5993 Point Mutation Unknown Splice Site ENU
    sa15531 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pan3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pan3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mRNA processing (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000571 Zinc finger, CCCH-type
    Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
    Family IPR030844 PAN2-PAN3 deadenylation complex subunit PAN3
    Homologous_superfamily IPR036855 Zinc finger, CCCH-type superfamily
    Domain IPR041332 Pan3 pseudokinase domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pan3-201 (1)    Ensembl 4368
    pan3-204 (1)    Ensembl 1409
    ncRNA pan3-003 (1)    Ensembl 2757
    pan3-004 (1)    Ensembl 555
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pan3 No data available
    MARKER RELATIONSHIPS
    pan3 Contained in: [BAC] CH211-140B10 (1)
    pan3 Encodes: [cDNA] MGC:171628 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001105692 (1)
    Genomic GenBank:BX571696 (1) 171175 bp
    Select Tool
    Polypeptide UniProtKB:E7EXP6 (1) 799 aa
    Sequence Information (all 14)
    ORTHOLOGY for pan3 ( Chr: 24 )
    CITATIONS (23)