ZFIN ID: ZDB-GENE-070912-659
Gene Name: nuclear factor of activated T cells 4
Gene Symbol: nfatc4    Nomenclature History

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Previous Names: si:dkeyp-66d1.4 (1), si:dkeyp-66d1.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in calcineurin-NFAT signaling cascade; cytokine production; and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytosol; nucleus; and transcription regulator complex. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human NFATC4 (nuclear factor of activated T cells 4).
Genome Resources: Alliance (1),  Gene:561682 (1),  Ensembl(GRCz11):ENSDARG00000054162 (2)
GENE EXPRESSION
All Expression Data: Fig. 5 from Pistocchi et al., 2013
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH nfatc4 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH nfatc4 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component cytosol (more)
Molecular Function DNA binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA nfatc4-201 (1)    Ensembl 3769
nfatc4-202 (1)    Ensembl 944
ncRNA nfatc4-003 (1)    Ensembl 861
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM nfatc4 No data available
MARKER RELATIONSHIPS
nfatc4 Contained in: [BAC] DKEYP-66D1 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_685091 (1)
Genomic GenBank:BX511153 (1) 129564 nt
Select Tool
Polypeptide UniProtKB:E7F059 (1) 865 aa
Sequence Information (all 14)
ORTHOLOGY for nfatc4 ( Chr: 2 )
CITATIONS (18)