Gene

abcb6b

ID
ZDB-GENE-070912-584
Name
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
Symbol
abcb6b Nomenclature History
Previous Names
  • si:dkey-7j20.1
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have ATPase-coupled heme transmembrane transporter activity and heme binding activity. Predicted to be involved in heme transport and transmembrane transport. Predicted to localize to integral component of membrane and vacuolar membrane. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Orthologous to human ABCB6 (ATP binding cassette subfamily B member 6 (Langereis blood group)).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With abcb6b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
dyschromatosis universalis hereditaria Alliance Dyschromatosis universalis hereditaria 3 615402
Microphthalmia, isolated, with coloboma 7 614497
Pseudohyperkalemia, familial, 2, due to red cell leak 609153
[Blood group, Langereis system] 111600
Associated With abcb6b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017871 ABC transporter, conserved site
Domain IPR003439 ABC transporter-like
Domain IPR003593 AAA+ ATPase domain
Domain IPR011527 ABC transporter type 1, transmembrane domain
Family IPR039421 Type I protein exporter
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036640 ABC transporter type 1, transmembrane domain superfamily
Domain Details Per Protein
Protein Length AAA+ ATPase domain ABC transporter, conserved site ABC transporter-like ABC transporter type 1, transmembrane domain ABC transporter type 1, transmembrane domain superfamily P-loop containing nucleoside triphosphate hydrolase Type I protein exporter
UniProtKB:B0S6D9 627
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations