ZFIN ID: ZDB-GENE-070912-575
Gene Name: Rho guanine nucleotide exchange factor (GEF) 4
Gene Symbol: arhgef4    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: si:dkey-74f15.3

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction. Predicted to localize to integral component of membrane. Orthologous to human ARHGEF4 (Rho guanine nucleotide exchange factor 4).
Genome Resources: Alliance (1),  Gene:559017 (1),  Ensembl(GRCz11):ENSDARG00000012914 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6828 Point Mutation Unknown Premature Stop ENU
sa12665 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13647 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17428 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19709 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19710 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25103 Point Mutation Unknown Premature Stop ENU
    sa32868 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39796 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39797 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39798 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39799 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44524 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH arhgef4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arhgef4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Cellular Component integral component of membrane (more)
    Molecular Function guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arhgef4-201 (1)    Ensembl 10438
    arhgef4-202 (1)    Ensembl 2917
    arhgef4-203 (1)    Ensembl 3431
    arhgef4-205 (1)    Ensembl 162
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef4 No data available
    MARKER RELATIONSHIPS
    arhgef4 Contained in: [BAC] DKEY-56J15 (1) (order this), DKEY-74F15 (1) (order this), DKEY-231J24 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_682312 (1) 2693 nt
    Genomic GenBank:CR788310 (1) 244700 nt Blast at MegaBLAST
    Polypeptide UniProtKB:E7FAH9 (1) 3063 aa
    Sequence Information (all 37)
    ORTHOLOGY for arhgef4 ( Chr: 2 )
    CITATIONS (16)