ZFIN ID: ZDB-GENE-070912-553
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Gene Name: zinc finger E-box binding homeobox 2a
Gene Symbol: zeb2a
Sequence Ontology ID : SO:0000704

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Previous Names: zeb2, sb:eu412, si:dkey-52o2.2, sip1a (1), Smad-interacting protein-1a (1), wu:fc92g08

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have metal ion binding activity and nucleic acid binding activity; involved in several processes, including chordate embryonic development, convergent extension, and negative regulation  ...
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 6 figures (26 images) from Thisse et al., 2005 [eu412]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010051Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la026845Tg Transgenic Insertion Unknown Unknown DNA
    la026846Tg Transgenic Insertion Unknown Unknown DNA
    la026847Tg Transgenic Insertion Unknown Unknown DNA
    la026848Tg Transgenic Insertion Unknown Unknown DNA
    sa16793 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa34655 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa34656 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 7 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH zeb2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Mowat-Wilson syndrome Mowat-Wilson syndrome 235730
    DISEASE ASSOCIATED WITH zeb2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process convergent extension involved in axis elongation (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR008598 (1)
  • InterPro:IPR013087 (1)
  • InterPro:IPR036236 (1)
    		•
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
    		•
  • Pfam:PF00096 (1)
  • Pfam:PF05605 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA zeb2a-004 (1) 940
    Select Tool
    mRNA zeb2a-201 (1) 4058
    Select Tool
    zeb2a-202 (1) 1351
    Select Tool
    zeb2a-203 (1) 448
    Select Tool
    zeb2a-204 (1) 859
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM zeb2a No data available
    MARKER RELATIONSHIPS
    zeb2aContained in: [BAC] DKEY-28L22 (order this), DKEY-52O2 (1) (order this), DKEY-253G9 (order this)
    zeb2aEncodes: [EST] eu412 (1), fc92g08
    [cDNA] MGC:175265 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001135104 (1) 5277bp
    Select Tool
    Genomic RefSeq:NW_018394754 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A0A286Y942 (1) 1242aa
    Select Tool
    Sequence Clusters UniGene:67155 (1)
    Sequence Information (all 40)
    OTHER zeb2a GENE PAGES
  • Alliance (1)
  • Gene:100003889 (1)
  • VEGA:OTTDARG00000025634 (1)
    • ORTHOLOGY for zeb2a (Chr: 9)
    CITATIONS (25)