ZFIN ID: ZDB-GENE-070912-449
Gene Name: MSL complex subunit 2a
Gene Symbol: msl2a    Nomenclature History

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Previous Names: msl2s, si:dkey-223d7.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in histone H4-K16 acetylation and protein ubiquitination. Predicted to localize to the MSL complex. Orthologous to human MSL2 (MSL complex subunit 2).
Genome Resources: Alliance (1),  Gene:564400 (1),  Ensembl(GRCz11):ENSDARG00000038909 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH msl2a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH msl2a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process histone H4-K16 acetylation (more)
Cellular Component MSL complex (more)
Molecular Function metal ion binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain IPR032043 E3 ubiquitin-protein ligase Msl2, zinc RING finger
Domain IPR032049 E3 ubiquitin-protein ligase Msl2, CXC domain
Domain IPR033467 Tesmin/TSO1-like CXC domain
Family IPR037922 E3 ubiquitin-protein ligase MSL2
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA msl2a-201 (1)    Ensembl 4040
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM msl2a No data available
MARKER RELATIONSHIPS
msl2a Contained in: [BAC] DKEY-223D7 (1) (order this)
msl2a Has Artifact: [EST] fq40e10
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001163298 (1)
Genomic GenBank:CR786576 (1) 202469 bp Blast at MegaBLAST
Polypeptide UniProtKB:B0V0X0 (1) 538 aa
Sequence Information (all 5)
ORTHOLOGY for msl2a ( Chr: 2 )
CITATIONS (15)