ZFIN ID: ZDB-GENE-070912-417
Gene Name: nardilysin a (N-arginine dibasic convertase)
Gene Symbol: nrd1a    Nomenclature History

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Previous Names: fk24c07, si:dkey-193b15.9 (1), wu:fk24c07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity and metalloendopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis involved in cellular protein catabolic process. Predicted to localize to mitochondrion. Orthologous to human NRDC (nardilysin convertase).
Genome Resources: Alliance (1),  Gene:565850 (1),  Ensembl(GRCz11):ENSDARG00000019596 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15383 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39882 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nrd1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nrd1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nrd1a-201 (1)    Ensembl 4046
    nrd1a-202 (1)    Ensembl 560
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nrd1a No data available
    MARKER RELATIONSHIPS
    nrd1a Contained in: [BAC] DKEY-193B15 (1) (order this)
    nrd1a Encodes: [EST] fk24c07
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005171326 (1)
    Genomic GenBank:BX470229 (1) 241018 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B0S6B9 (1) 1091 aa
    Sequence Information (all 18)
    ORTHOLOGY for nrd1a ( Chr: 2 )
    CITATIONS (16)