Gene

pde4ca

ID

ZDB-GENE-070912-373

Name

phosphodiesterase 4C, cAMP-specific a

Symbol

pde4ca Nomenclature History

Previous Names

Pde43 (1)
pde4c
im:7160317
si:dkey-149i17.5

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have 3',5'-cyclic-AMP phosphodiesterase activity. Predicted to be involved in signal transduction. Orthologous to human PDE4C (phosphodiesterase 4C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7160317 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pde4ca Human Ortholog

No data available

Associated With pde4ca Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site
Domain	IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
Domain	IPR003607	HD/PDEase domain
Domain	IPR040844	Phosphodiesterase 4 upstream conserved regions (UCR)
Family	IPR023088	3'5'-cyclic nucleotide phosphodiesterase
Homologous_superfamily	IPR036971	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	3'5'-cyclic nucleotide phosphodiesterase	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily	3'5'-cyclic nucleotide phosphodiesterase, conserved site	HD/PDEase domain	Phosphodiesterase 4 upstream conserved regions (UCR)
UniProtKB:A0A8M9PPY4 InterPro	742
UniProtKB:A0A8M2BAJ1 InterPro	586
UniProtKB:A0A8M9Q0N3 InterPro	717
UniProtKB:A0A8M9P0C0 InterPro	742
UniProtKB:A0A8M9PXB7 InterPro	639

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pde4ca-201 (1) Ensembl	Ensembl	2,091 nt	Select Tool ZFIN BLAST
mRNA	pde4ca-202 (1) Ensembl	Ensembl	5,860 nt	Select Tool
mRNA	pde4ca-203 (1) Ensembl	Ensembl	348 nt	Select Tool
ncRNA	pde4ca-003 (1) Ensembl	Ensembl	898 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations