ZFIN ID: ZDB-GENE-070912-293
Gene Name: cytochrome P450, family 7, subfamily B, polypeptide 1
Gene Symbol: cyp7b1
Previous Names: cyp7c1, si:ch211-39l18.4
Location: Chr: 2   Details
Nomenclature History
GENE EXPRESSION No data available
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: cyp7b1sa1217/sa1217(Tupfel long fin)

Allele Type Mutagen Suppliers
la023703Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1217 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Phenotype of Human Orthologue OMIM Phenotype ID
    Bile acid synthesis defect, congenital, 3 613812
    Spastic paraplegia 5A, autosomal recessive 270800
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function heme binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002403 (1)
  • InterPro:IPR017972 (1)
  • InterPro:IPR024204 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp7c1-001 (1) 1707
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp7b1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp7b1 Contained in: [BAC] CH211-39L18 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_693936 (1) 2292 bp
    Genomic GenBank:BX324211 (1) 91947 bp
    Select Tool
    Polypeptide UniProtKB:E7FEI0 (1) 504 aa
    Sequence Information (all 5)
    OTHER cyp7b1 GENE PAGES
  • Gene:570455 (1)
  • VEGA:OTTDARG00000025133 (1)
  • Ensembl(Zv9):ENSDARG00000008858 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish cyp7b1 2  
    Human CYP7B1 8 (8q21.3)
  • OMIM:603711
  • Gene:9420
  • Mouse Cyp7b1 3 ( 4.98 cM)
  • MGI:104978
  • Gene:13123
  • Orthology Details
    CITATIONS (15)