ZFIN ID: ZDB-GENE-070912-21
Gene Name: ArfGAP with dual PH domains 2
Gene Symbol: adap2    Nomenclature History

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Previous Names: si:ch211-11k18.11 (1), si:ch73-33i10.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity; metal ion binding activity; and phosphatidylinositol bisphosphate binding activity. Involved in atrioventricular valve development; heart jogging; and heart looping. Predicted to localize to intracellular membrane-bounded organelle and plasma membrane. Is expressed in several structures, including digestive system; gonad; head; heart; and skeletal muscle. Orthologous to human ADAP2 (ArfGAP with dual PH domains 2).
Genome Resources: Alliance (1),  Gene:100331455 (1),  Ensembl(GRCz11):ENSDARG00000070565 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6893 Point Mutation Unknown Splice Site ENU
sa9788 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40066 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-adap2 N/A 1
    MO2-adap2 N/A 1
    DISEASE ASSOCIATED WITH adap2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH adap2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process atrioventricular valve development (more)
    Cellular Component intracellular membrane-bounded organelle (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA adap2-201 (1)    Ensembl 1291
    ncRNA adap2-002 (1)    Ensembl 837
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM adap2 No data available
    MARKER RELATIONSHIPS
    adap2 Contained in: [BAC] CH73-33I10 (1), CH211-11K18 (1)
    [Fosmid] CH1073-455J6 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_021473800 (1)
    Genomic GenBank:BX511232 171843 nt
    Select Tool
    Polypeptide UniProtKB:E9QE78 (1) 378 aa
    Sequence Information (all 11)
    ORTHOLOGY for adap2 ( Chr: 3 )
    CITATIONS (16)