ZFIN ID: ZDB-GENE-050517-4
Gene Name: ATP-binding cassette, sub-family A (ABC1), member 4b
Gene Symbol: abca4b    Nomenclature History

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Previous Name: si:ch211-195i6.4 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have ATPase-coupled intramembrane lipid transporter activity; ATPase-coupled transmembrane transporter activity; and phospholipid transporter activity. Predicted to be involved in lipid transport. Predicted to localize to intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in fundus dystrophy and retinal degeneration (multiple). Orthologous to human ABCA4 (ATP binding cassette subfamily A member 4).
Genome Resources: Alliance (1),  Gene:555506 (1),  Ensembl(GRCz11):ENSDARG00000062661 (2)
GENE EXPRESSION No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH abca4b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
age related macular degeneration 2 Alliance {Macular degeneration, age-related, 2} 153800
cone-rod dystrophy 3 Alliance Cone-rod dystrophy 3 604116
retinitis pigmentosa 19 Alliance Retinitis pigmentosa 19 601718
Stargardt disease Alliance Fundus flavimaculatus 248200
Retinal dystrophy, early-onset severe 248200
Stargardt disease 1 248200
DISEASE ASSOCIATED WITH abca4b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process transmembrane transport (more)
Cellular Component integral component of membrane (more)
Molecular Function ATPase activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA abca4b-202 (1)    Ensembl 7493
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM abca4b No data available
MARKER RELATIONSHIPS
abca4b Contained in: [BAC] CH211-195I6 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_005163328 (1) 7400 nt
Genomic GenBank:CR450809 (1) 206746 nt Blast at MegaBLAST
Polypeptide UniProtKB:F1R045 (1) 2327 aa
Sequence Information (all 14)
ORTHOLOGY for abca4b ( Chr: 2 )
CITATIONS (22)