Gene

si:ch211-195h23.3

ID
ZDB-GENE-070912-174
Name
si:ch211-195h23.3
Symbol
si:ch211-195h23.3 Nomenclature History
Previous Names
  • CARD-rel (1)
  • Gene2604 (1)
  • Gene38616 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase activity involved in apoptotic signaling pathway and cysteine-type endopeptidase activity involved in execution phase of apoptosis. Involved in negative regulation of NF-kappaB transcription factor activity. Localizes to nucleus. Is expressed in kidney and spleen. Orthologous to human CARD8 (caspase recruitment domain family member 8).
Genome Resources
Note
None
Expression
All Expression Data
from Chang et al., 2010
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With si:ch211-195h23.3 Human Ortholog
No data available
Associated With si:ch211-195h23.3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001315 CARD domain
Domain IPR025307 FIIND domain
Domain IPR033516 CARD8/ASC/NALP1, CARD domain
Family IPR002398 Peptidase C14 family
Homologous_superfamily IPR011029 Death-like domain superfamily
Domain Details Per Protein
Protein Length CARD8/ASC/NALP1, CARD domain CARD domain Death-like domain superfamily FIIND domain Peptidase C14 family
UniProtKB:B0V1H3 478
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations