Gene

kirrel1b

ID
ZDB-GENE-070912-173
Name
kirre like nephrin family adhesion molecule 1b
Symbol
kirrel1b Nomenclature History
Previous Names
  • kirrelb
  • Neph1b (1)
  • si:ch211-195h23.2
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable cell adhesion molecule binding activity. Acts upstream of or within glomerular basement membrane development; glomerular visceral epithelial cell development; and pronephric duct development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cell-cell junction. Predicted to be integral component of plasma membrane. Is expressed in brain and pronephric glomerulus. Human ortholog(s) of this gene implicated in nephrotic syndrome type 23. Orthologous to human KIRREL1 (kirre like nephrin family adhesion molecule 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Neumann-Haefelin et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kirrel1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nephrotic syndrome type 23 Alliance Nephrotic syndrome, type 23 619201
Associated With kirrel1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Domain IPR013162 CD80-like, immunoglobulin C2-set
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length CD80-like, immunoglobulin C2-set Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2
UniProtKB:B0V1H1 778
UniProtKB:B3DHL7 790
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations