Gene

gzm3.4

ID
ZDB-GENE-070912-136
Name
granzyme 3, tandem duplicate 4
Symbol
gzm3.4 Nomenclature History
Previous Names
  • si:ch211-165b19.9 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in asthma; atopic dermatitis; hypertrophic cardiomyopathy; and sarcoidosis. Orthologous to several human genes including CTSG (cathepsin G); CMA1 (chymase 1); and GZMB (granzyme B).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gzm3.4 Human Ortholog
No data available
Associated With gzm3.4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001254 Serine proteases, trypsin domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Domain Details Per Protein
Protein Length Peptidase S1A, chymotrypsin family Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain
UniProtKB:A8WIQ5 251
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations