Gene
hbegfb
- ID
- ZDB-GENE-070820-6
- Name
- heparin-binding EGF-like growth factor b
- Symbol
- hbegfb Nomenclature History
- Previous Names
-
- hbegf
- zgc:165443
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable epidermal growth factor receptor binding activity and growth factor activity. Acts upstream of or within heart contraction. Predicted to be located in membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. Orthologous to human HBEGF (heparin binding EGF like growth factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from El-Brolosy et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Friedrichs et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Diphtheria, susceptibility to} |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EGF-like domain | Epidermal growth factor receptor ligand |
|---|---|---|---|
|
UniProtKB:F1QKE6
|
113 | ||
|
UniProtKB:Q6NY79
|
239 | ||
|
UniProtKB:A0A2R8RUB3
|
232 | ||
|
UniProtKB:A7E275
|
208 | ||
|
UniProtKB:F1QEL2
|
263 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
hbegfb-201
(1)
|
857 nt | |
| mRNA |
hbegfb-202
(1)
|
1651 nt |
Interactions and Pathways
No data available
Plasmids
No data available