Gene

adamts18

ID
ZDB-GENE-070815-1
Name
ADAM metallopeptidase with thrombospondin type 1 motif, 18
Symbol
adamts18 Nomenclature History
Previous Names
  • sb:eu2468
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization. Predicted to localize to extracellular matrix. Is expressed in several structures, including anterior axial hypoblast; digestive system; nervous system; neural keel; and pleuroperitoneal region. Orthologous to human ADAMTS18 (ADAM metallopeptidase with thrombospondin type 1 motif 18).
Genome Resources
Note
None
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Lu et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adamts18 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Microcornea, myopic chorioretinal atrophy, and telecanthus 615458
Associated With adamts18 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR002870 Peptidase M12B, propeptide
Domain IPR010294 ADAM-TS Spacer 1
Domain IPR010909 PLAC
Domain IPR041645 ADAM cysteine-rich domain 2
Family IPR013273 ADAMTS/ADAMTS-like
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Domain Details Per Protein
Protein Length ADAM cysteine-rich domain 2 ADAMTS/ADAMTS-like ADAM-TS Spacer 1 Metallopeptidase, catalytic domain superfamily Peptidase M12B, ADAM/reprolysin Peptidase M12B, propeptide PLAC Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:A0A2R8QKK2 210
UniProtKB:E7FEJ5 1244
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations