Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-070815-1
Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif, 18
Gene Symbol: adamts18
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION No data available
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la016124Tg, la016125Tg, la026069Tg, la026070Tg, sa12213 (all 7) expand
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Microcornea, myopic chorioretinal atrophy, and telecanthus 615458
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component extracellular matrix (more)
Molecular Function metalloendopeptidase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000884 (1)
  • InterPro:IPR001590 (1)
  • InterPro:IPR002870 (1)
  • InterPro:IPR010294 (1)
  • InterPro:IPR010909 (1)
  • InterPro:IPR013273 (1)
  • InterPro:IPR024079 (1)
  • PROSITE:PS50092 (1)
  • PROSITE:PS50215 (1)
  • PROSITE:PS50900 (1)
  • Pfam:PF00090 (1)
  • Pfam:PF01421 (1)
  • Pfam:PF01562 (1)
  • Pfam:PF05986 (1)
  • Pfam:PF08686 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA adamts18-001 (1) 3503
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM adamts18 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    adamts18 Contained in: [BAC] DKEY-59H7, DKEY-273O8 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001919031 (1) 4545 bp
    Genomic GenBank:BX511133 (1) 157916 bp
    Select Tool
    Polypeptide UniProtKB:E7FEJ5 (1) 1244 aa
    Sequence Clusters UniGene:129936 (1)
    Sequence Information (all 9)
    OTHER adamts18 GENE PAGES
  • Gene:100150128 (1)
  • VEGA:OTTDARG00000035316 (1)
  • Ensembl(Zv9):ENSDARG00000001999 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish adamts18 7  
    Human ADAMTS18 16 (16q23)
  • OMIM:607512
  • Gene:170692
  • Orthology Details
    CITATIONS (14)