Gene

adamts13

ID
ZDB-GENE-070814-7
Name
ADAM metallopeptidase with thrombospondin type 1 motif, 13
Symbol
adamts13 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization. Predicted to localize to extracellular matrix. Human ortholog(s) of this gene implicated in thrombotic thrombocytopenic purpura. Orthologous to human ADAMTS13 (ADAM metallopeptidase with thrombospondin type 1 motif 13).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adamts13 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
thrombotic thrombocytopenic purpura Alliance Thrombotic thrombocytopenic purpura, hereditary 274150
Associated With adamts13 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000859 CUB domain
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR041645 ADAM cysteine-rich domain 2
Family IPR013273 ADAMTS/ADAMTS-like
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR035914 Spermadhesin, CUB domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Domain Details Per Protein
Protein Length ADAM cysteine-rich domain 2 ADAMTS/ADAMTS-like CUB domain Metallopeptidase, catalytic domain superfamily Peptidase M12B, ADAM/reprolysin Spermadhesin, CUB domain superfamily Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:F1R2Z7 1364
UniProtKB:A0A286Y999 1498
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations