Gene
adamts9
- ID
- ZDB-GENE-070814-6
- Name
- ADAM metallopeptidase with thrombospondin type 1 motif, 9
- Symbol
- adamts9 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Is predicted to enable metalloendopeptidase activity. Involved in extracellular matrix organization. Acts upstream of or within endocrine pancreas development and pancreas regeneration. Predicted to be located in extracellular region. Is expressed in several structures, including digestive system; gonad; immune system; lepidotrichium; and nervous system. Used to study scoliosis. Orthologous to human ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
scoliosis | adamts9stl316/stl316 | standard conditions | Gray et al., 2020 |
scoliosis | adamts9stl756/stl756 | standard conditions | Gray et al., 2020 |
scoliosis | adamts9stl336/stl336 | standard conditions | Gray et al., 2020 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001590 | Peptidase M12B, ADAM/reprolysin |
Domain | IPR002870 | Peptidase M12B, propeptide |
Family | IPR013273 | ADAMTS/ADAMTS-like |
Homologous_superfamily | IPR024079 | Metallopeptidase, catalytic domain superfamily |
Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
Domain Details Per Protein
Protein | Length | ADAMTS/ADAMTS-like | Metallopeptidase, catalytic domain superfamily | Peptidase M12B, ADAM/reprolysin | Peptidase M12B, propeptide | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:F1R6Q4
|
1461 | ||||||
UniProtKB:E7F6N6
|
1443 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
adamts9-201
(1)
|
10402 nt |
Interactions and Pathways
No data available
Plasmids
No data available