ZFIN ID: ZDB-GENE-070810-2
Gene Name: ADAM metallopeptidase domain 23a
Gene Symbol: adam23a    Nomenclature History

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Previous Names: wu:fj40f01, wu:fq14a08

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to the integral component of membrane. Is expressed in central nervous system. Orthologous to human ADAM23 (ADAM metallopeptidase domain 23).
Genome Resources: Alliance (1),  Gene:794175 (1),  Ensembl(GRCz11):ENSDARG00000062323 (2)
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Directly Submitted Expression Data: 4 figures (10 images) from Rauch et al., 2003 [fq14a08]
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH adam23a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH adam23a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component integral component of membrane (more)
Molecular Function metalloendopeptidase activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001590 Peptidase M12B, ADAM/reprolysin
Domain IPR001762 Disintegrin domain
Domain IPR002870 Peptidase M12B, propeptide
Domain IPR006586 ADAM, cysteine-rich domain
Conserved_site IPR013032 EGF-like, conserved site
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Domain IPR034027 Reprolysin domain, adamalysin-type
Homologous_superfamily IPR036436 Disintegrin domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA adam23a-201 (1)    Ensembl 2703
adam23a-202 (1)    Ensembl 3194
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM adam23a No data available
MARKER RELATIONSHIPS
adam23a Contained in: [BAC] CH73-187F10
adam23a Encodes: [EST] fj40f01, fq14a08 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_001923227 (1) 4013 bp
Genomic GenBank:CT009620 (1) 95528 bp
Select Tool
Polypeptide UniProtKB:F8W3T1 (1) 785 aa
Sequence Information (all 18)
ORTHOLOGY for adam23a ( Chr: 6 )
CITATIONS (19)