ZFIN ID: ZDB-GENE-070810-1
Gene Name: ADAM metallopeptidase domain 22
Gene Symbol: adam22    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 61. Orthologous to human ADAM22 (ADAM metallopeptidase domain 22).
Genome Resources: Alliance (1),  Gene:100126805 (1),  Ensembl(GRCz11):ENSDARG00000060532 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6446 Point Mutation Unknown Splice Site ENU
sa14978 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19148 Point Mutation Unknown Splice Site ENU
    sa36238 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH adam22 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    early infantile epileptic encephalopathy 61 Alliance ?Epileptic encephalopathy, early infantile, 61 617933
    DISEASE ASSOCIATED WITH adam22 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function metalloendopeptidase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA adam22-201 (1)    Ensembl 4159
    adam22-202 (1)    Ensembl 1440
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM adam22 No data available
    MARKER RELATIONSHIPS
    adam22 Contained in: [BAC] CH211-246D10
    adam22 Has Artifact: [cDNA] MGC:173905
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001111085 (1)
    Genomic GenBank:CR848685 (1) 149329 nt
    Select Tool
    Polypeptide UniProtKB:F1QF43 (1) 918 aa
    Sequence Information (all 19)
    ORTHOLOGY for adam22 ( Chr: 16 )
    CITATIONS (16)