ZFIN ID: ZDB-GENE-070801-4
Gene Name: hephaestin-like 1a
Gene Symbol: hephl1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: hephl1, zgc:165649

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have ferroxidase activity. Predicted to be involved in iron ion homeostasis and iron ion transport. Predicted to localize to plasma membrane. Orthologous to human HEPHL1 (hephaestin like 1).
Genome Resources: Alliance (1),  Gene:561607 (1),  Ensembl(GRCz11):ENSDARG00000059231 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Segmentation:20-25 somites (19.0h-22.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa42469 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hephl1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Abnormal hair, joint laxity, and developmental delay 261990
    DISEASE ASSOCIATED WITH hephl1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function copper ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hephl1a-201 (1)    Ensembl 1974
    hephl1a-203 (1)    Ensembl 5525
    ncRNA hephl1a-002 (1)    Ensembl 684
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hephl1a No data available
    MARKER RELATIONSHIPS
    hephl1a Contained in: [BAC] CH73-203K13 (1)
    [Fosmid] CH1073-371N23 (1)
    hephl1a Encodes: [cDNA] MGC:165649 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001105110 (1) 1994 nt
    Genomic GenBank:CU896646 (1) 82708 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8PX52 (1) 1124 aa
    Sequence Information (all 19)
    ORTHOLOGY for hephl1a ( Chr: 15 )
    CITATIONS (23)