ZFIN ID: ZDB-GENE-070720-17
Gene Name: polo-like kinase 2b (Drosophila)
Gene Symbol: plk2b    Nomenclature History

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Previous Names: plk2, zgc:165644 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Involved in sprouting angiogenesis. Predicted to localize to cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in endothelial cell and vasculature. Orthologous to human PLK2 (polo like kinase 2).
Genome Resources: Alliance (1),  Gene:565576 (1),  Ensembl(GRCz11):ENSDARG00000019130 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
as53 Complex Unknown Unknown CRISPR
sa30900 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41164 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-plk2b 2
    CRISPR2-plk2b 2
    MO1-plk2b N/A 1
    MO2-plk2b N/A 2
    MO3-plk2b N/A 1
    DISEASE ASSOCIATED WITH plk2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH plk2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process sprouting angiogenesis (more)
    Cellular Component centrosome (more)
    Molecular Function ATP binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA plk2b-201 (1)    Ensembl 2415
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM plk2b No data available
    MARKER RELATIONSHIPS
    plk2b Contained in: [BAC] DKEY-190G11 (1) (order this)
    plk2b Encodes: [cDNA] MGC:165644 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001099245 (1) 2440 nt
    Genomic GenBank:BX510928 (1) 197947 nt
    Select Tool
    Polypeptide UniProtKB:A6H8T5 (1) 657 aa
    Sequence Information (all 12)
    ORTHOLOGY for plk2b ( Chr: 8 )
    CITATIONS (24)