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ZIRC
ZFIN ID: ZDB-GENE-070719-9
Gene Name: xanthine dehydrogenase
Gene Symbol: xdh    Nomenclature History

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Previous Name: im:7146167

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have flavin adenine dinucleotide binding activity and xanthine dehydrogenase activity. Predicted to be involved in xanthine catabolic process. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in several diseases, including Lesch-Nyhan syndrome; cardiovascular system disease (multiple); chronic kidney disease; hyperuricemia; and xanthinuria. Is expressed in neural crest cell and xanthoblast. Orthologous to human XDH (xanthine dehydrogenase).
Genome Resources: Alliance (1),  Gene:560486 (1),  Ensembl(GRCz11):ENSDARG00000055240 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7146167]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH xdh HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
xanthinuria Alliance Xanthinuria, type I 278300
DISEASE ASSOCIATED WITH xdh VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component cytosol (more)
Molecular Function 2 iron, 2 sulfur cluster binding (more)
GO Terms (all 15)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA xdh-201 (1)    Ensembl 5683
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM xdh No data available
MARKER RELATIONSHIPS
xdh Contained in: [BAC] CH211-132F19 (order this)
xdh Encodes: [EST] IMAGE:7146167 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_683891 (1)
Genomic GenBank:BX323819 (1) 178951 bp
Select Tool
Polypeptide UniProtKB:A0A2R8Q1T4 (1) 1381 aa
Sequence Clusters UniGene:93222 (1)
Sequence Information (all 11)
ORTHOLOGY for xdh ( Chr: 17 )
CITATIONS (28)