ZFIN ID: ZDB-GENE-070718-4
Gene Name: oculocutaneous albinism II
Gene Symbol: oca2
Sequence Ontology ID : SO:0000704

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Previous Name: P gene

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 1 from Seberg et al., 2017
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015914Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9009 Point Mutation Unknown Premature Stop ENU
    sa11052 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa20754 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33907 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33908 Point Mutation Unknown Splice Site ENU
    w77 Complex Unknown Unknown ENU
    Targeting reagents: MO1-oca2 (1)
    PHENOTYPE
    Data: 4 figures from 2 publications
    Observed in: dorsal larval melanophore stripe iridophore, head melanocyte, melanocyte melanosome, melanocyte (all 7) expand
    DISEASE ASSOCIATED WITH oca2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    oculocutaneous albinism Albinism, brown oculocutaneous 203200
    Albinism, oculocutaneous, type II 203200
    [Skin/hair/eye pigmentation 1, blond/brown hair] 227220
    [Skin/hair/eye pigmentation 1, blue/nonblue eyes] 227220
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process iridophore differentiation (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004680 (1)
  • InterPro:IPR020846 (1)
  • Pfam:PF03600 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA oca2-001 (1) 1987
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM oca2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    oca2Contained in: [BAC] DKEY-20L10 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_690715 (1) 3433bp
    Genomic GenBank:AL935047 (1) 201929bp Blast at MegaBLAST
    Polypeptide UniProtKB:E7EXF7 (1) 834aa
    Sequence Clusters UniGene:115319 (1)
    Sequence Information (all 9)
    OTHER oca2 GENE PAGES
  • Gene:567419 (1)
  • VEGA:OTTDARG00000034623 (1)
  • Ensembl(GRCz10):ENSDARG00000061303 (1)
  • ORTHOLOGY for oca2 (Chr: 6)
    CITATIONS (22)