ZFIN ID: ZDB-GENE-070718-2
Gene Name: tyrosinase-related protein 1a
Gene Symbol: tyrp1a
Sequence Ontology ID : SO:0000704

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Previous Name: oca3

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  eye, female organism, male organism, melanoblast (all 6) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
dtva6 Point Mutation Unknown Missense ENU
Targeting reagents: MO1-tyrp1a (1), MO2-tyrp1a (1)
PHENOTYPE
Data: 3 figures from Krauss et al., 2014
Observed in: melanocyte melanosome, melanocyte, melanophore stripe, whole organism
DISEASE ASSOCIATED WITH tyrp1a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
oculocutaneous albinism Albinism, oculocutaneous, type III 203290
[Skin/hair/eye pigmentation, variation in, 11 (Melanesian blond hair)] 612271
GENE ONTOLOGY
Ontology GO Term
Biological Process melanosome organization (more)
Cellular Component integral component of membrane (more)
Molecular Function copper ion binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002227 (1)
  • InterPro:IPR008922 (1)
  • InterPro:IPR015559 (1)
  • PROSITE:PS00497 (1)
  • PROSITE:PS00498 (1)
  • Pfam:PF00264 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tyrp1a-001 (1) 2192
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tyrp1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_017357250 (1) 2456bp
    Genomic GenBank:CABZ01079373 (1) 6623bp
    Polypeptide UniProtKB:A9JSV0 (1) 582aa
    Sequence Clusters UniGene:117067 (1)
    Sequence Information (all 13)
    OTHER tyrp1a GENE PAGES
  • Gene:100333145 (1)
  • VEGA:OTTDARG00000044006 (1)
  • Ensembl(GRCz10):ENSDARG00000029204 (1)
  • ORTHOLOGY for tyrp1a (Chr: 7)
    CITATIONS (16)