ZFIN ID: ZDB-GENE-070713-6
Gene Name: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
Gene Symbol: gnai3    Nomenclature History

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Previous Name: Galpha i3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to localize to heterotrimeric G-protein complex. Is expressed in barbel; brain; gill; lip; and sensory system. Orthologous to human GNAI3 (G protein subunit alpha i3).
Genome Resources: Alliance (1),  Gene:100006888 (1),  Ensembl(GRCz11):ENSDARG00000030644 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026457Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21295 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gnai3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Auriculocondylar syndrome 1 602483
    DISEASE ASSOCIATED WITH gnai3 VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gnai3-201 (1)    Ensembl 1798
    gnai3-202 (1)    Ensembl 799
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gnai3 No data available
    MARKER RELATIONSHIPS
    gnai3 Contained in: [BAC] CH211-77C7 (1)
    gnai3 Encodes: [cDNA] MGC:174876 (1), MGC:198365 (1), MGC:198369 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001111250 (1) 1931 nt
    Genomic GenBank:CU462975 (1) 148505 nt
    Select Tool
    Polypeptide UniProtKB:A9JTC8 (1) 354 aa
    Sequence Information (all 18)
    ORTHOLOGY for gnai3 ( Chr: 8 )
    CITATIONS (29)