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ZIRC
ZFIN ID: ZDB-GENE-070713-2
Gene Name: eph receptor B2a
Gene Symbol: ephb2a    Nomenclature History

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Previous Names: ephb2 (1), si:ch73-160e9.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have transmembrane-ephrin receptor activity. Involved in blood vessel development; convergent extension; and ephrin receptor signaling pathway. Predicted to localize to the integral component of plasma membrane; neuron projection; and receptor complex. Human ortholog(s) of this gene implicated in blood platelet disease. Is expressed in dorsal aorta; optic cup; pronephric glomerular capillary; retina; and somite. Orthologous to human EPHB2 (EPH receptor B2).
Genome Resources: Alliance (1),  Gene:562176 (1),  Ensembl(GRCz11):ENSDARG00000037373 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24316 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ephb2a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ephb2a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Bleeding disorder, platelet-type, 22 618462
    {Prostate cancer/brain cancer susceptibility, somatic} 603688
    DISEASE ASSOCIATED WITH ephb2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood vessel development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 21)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ephb2a-201 (1)    Ensembl 6435
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ephb2a No data available
    MARKER RELATIONSHIPS
    ephb2a Contained in: [BAC] CH73-160E9 (1) (order this), DKEY-68L7 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001919987 (1) 4613 bp
    Genomic GenBank:BX005235 (1) 211618 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1RCR4 (1) 1015 aa
    Sequence Information (all 17)
    ORTHOLOGY for ephb2a ( Chr: 23 )
    CITATIONS (37)