ZFIN ID: ZDB-GENE-070712-2
Gene Name: CREB regulated transcription coactivator 3
Gene Symbol: crtc3    Nomenclature History

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Previous Name: zfTorc3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have cAMP response element binding protein binding activity. Involved in response to hypoxia. Predicted to localize to cytoplasm and nucleus. Is expressed in head. Orthologous to human CRTC3 (CREB regulated transcription coactivator 3).
Genome Resources: Alliance (1),  Gene:570024 (1),  Ensembl(GRCz11):ENSDARG00000052114 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa5443 Point Mutation Unknown Premature Stop ENU
sa8737 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9161 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41008 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-crtc3 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH crtc3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH crtc3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to hypoxia (more)
    Cellular Component cytoplasm (more)
    Molecular Function cAMP response element binding protein binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA crtc3-004 (1) 3153
    crtc3-202 (1)    Ensembl 480
    crtc3-203 (1)    Ensembl 8364
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM crtc3 No data available
    MARKER RELATIONSHIPS No data available
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005166492 (1) 5470 nt
    Polypeptide UniProtKB:E7F3Z5 (1) 535 aa
    Sequence Information (all 9)
    ORTHOLOGY for crtc3 ( Chr: 7 )
    CITATIONS (17)