ZFIN ID: ZDB-GENE-070705-88
Gene Name: dipeptidyl-peptidase 6b
Gene Symbol: dpp6b    Nomenclature History

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Previous Name: si:ch211-198f16.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have serine-type peptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; autosomal dominant non-syndromic intellectual disability 33; and spinal muscular atrophy. Orthologous to human DPP6 (dipeptidyl peptidase like 6).
Genome Resources: Alliance (1),  Gene:566832 (1),  Ensembl(GRCz11):ENSDARG00000024744 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014816Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023442Tg Transgenic Insertion Unknown Unknown DNA
    sa14761 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19693 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25100 Point Mutation Unknown Premature Stop ENU
    sa31263 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dpp6b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal dominant non-syndromic intellectual disability 33 Alliance Mental retardation, autosomal dominant 33 616311
    {Ventricular fibrillation, paroxysmal familial, 2} 612956
    DISEASE ASSOCIATED WITH dpp6b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function serine-type peptidase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dpp6b-201 (1)    Ensembl 3893
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dpp6b No data available
    MARKER RELATIONSHIPS
    dpp6b Contained in: [BAC] CH73-86D22 (1), CH211-175P12 (1), CH211-198F16 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001115122 (1) 4336 nt
    Genomic GenBank:BX005226 (1) 176642 nt
    Select Tool
    Polypeptide UniProtKB:E7F5R8 (1) 857 aa
    Sequence Information (all 17)
    ORTHOLOGY for dpp6b ( Chr: 2 )
    CITATIONS (19)