ZFIN ID: ZDB-GENE-070705-73
Gene Name: myosin, heavy polypeptide 1.2, skeletal muscle
Gene Symbol: myhz1.2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fmyhc1.2 (1), ns:zf-e523, si:ch211-158m24.8

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Predicted to localize to the myosin complex. Human ortholog(s) of this gene implicated in disease of cellular proliferation; distal arthrogryposis; inclusion body myositis; and multiple pterygium syndrome. Is expressed in cephalic musculature and trunk. Orthologous to several human genes including MYH1 (myosin heavy chain 1).
Genome Resources: Alliance (1),  Gene:799300 (1),  Ensembl(GRCz11):ENSDARG00000067995 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH myhz1.2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH myhz1.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component myosin complex (more)
Molecular Function actin binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR001609 Myosin head, motor domain
Domain IPR002928 Myosin tail
Domain IPR004009 Myosin, N-terminal, SH3-like
Homologous_superfamily IPR008989 Myosin S1 fragment, N-terminal
Homologous_superfamily IPR027401 Myosin IQ motif-containing domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA myhz1.2-201 (1)    Ensembl 6016
Browsers: UCSCEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM myhz1.2
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(myhz1.2:EGFP) myhz1.2 EGFP Danio rerio 1 1
Tg(myhz1.2:GFP) myhz1.2 GFP Danio rerio 1 3
MARKER RELATIONSHIPS
myhz1.2 Contained in: [BAC] CH211-158M24 (1)
myhz1.2 Encodes: [EST] zf-e523
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001161446 (1) 5975 bp
Genomic GenBank:BX510649 (1) 189844 bp
Select Tool
Polypeptide UniProtKB:B8A561 (1) 1937 aa
Sequence Information (all 19)
ORTHOLOGY for myhz1.2 ( Chr: 5 )
CITATIONS (28)