Gene

man1b1b

ID
ZDB-GENE-070705-482
Name
mannosidase, alpha, class 1B, member 1b
Symbol
man1b1b Nomenclature History
Previous Names
  • man1b1
  • si:dkey-61l1.3
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in N-glycan processing and ubiquitin-dependent ERAD pathway. Predicted to localize to endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human MAN1B1 (mannosidase alpha class 1B member 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With man1b1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
non-syndromic intellectual disability Alliance Rafiq syndrome 614202
Associated With man1b1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001382 Glycoside hydrolase family 47
Homologous_superfamily IPR012341 Six-hairpin glycosidase-like superfamily
Homologous_superfamily IPR036026 Seven-hairpin glycosidases
Domain Details Per Protein
Protein Length Glycoside hydrolase family 47 Seven-hairpin glycosidases Six-hairpin glycosidase-like superfamily
UniProtKB:A0A2R8Q2C1 620
UniProtKB:A5WWD5 632
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations